User blog comment:UTF/UTF's belated Q&A Blog./@comment-30480843-20170525231041/@comment-6380028-20170525232535

There's always Bowser VS Ganon, where most people here think Bowser VS Dedede and Ganon VS Dracula. Besides that, Scrooge probably could have fought Wario.

Favorites: Mario VS Sonic, Green Arrow VS Hawkeye/Iron Man VS Lex Luthor, Hulk VS Doomsday/Deadpool VS Pinkie. Least: Justin VS Rebecca, none for S2, Bowser VS Ganon.