Board Thread:VS Debates/@comment-5898946-20170225211539/@comment-26140879-20170225231531

Sam just simply faces more dangerous foes than Duke, his Serious Damage and Serious Speed both last longer than Duke's steroids(and don't restrict him to melee combat if we go by DNF's sterioids), and he carries around these things. However, some of Duke's haxxy weapons like the shrink ray could prove troublesome for Sam.

All in all, I think Sam would win.