Talk:Iron Man VS Lex Luthor/@comment-25182985-20150412213526/@comment-25430354-20150412220111

Wolverine (Marvel) vs Freddy Krueger (Nightmare on Elm Street)

Hulk (Marvel) vs Broly (DBZ) or Doomsday (DC)

T.J. Combo (Killer Instinct) vs Balrog (Street Fighter)

At the moment can't think of too much else, though I don't think this would technically be the first hero vs villain situation of DB. Guts vs Nightmare is certainly one, and Starscream vs RD might count.